Early prophase: the DNA and centrioles duplicate and the centioles move and form the mitotic spindle. Middle prophase: microtubles from the spindle attach to the chromosomes. Late prophase: the chromosomes move to the equatorial plane.
Allosteric regulation occurs at these points where the concentration of the substrate and/or products is important for the activation and inhibition of the enzyme.
<span>The process when molecules tend to move from an area of high concentration to an area of low concentration is diffusion! I hope I helped :D</span>
