Question

Lithium diisopropylamide [(CH3)2CH]2NLi, referred to as LDA, enjoys many uses as a strong base in synthetic organic chemistry. It is customarily prepared by the reaction of diisopropylamine [(CH3)2CH]2NH with butyllithium. Draw the products of the reactions in the appropriate boxes and select the acid, base, conjugate acid, and conjugate base. Be sure to answer all parts.

Answer 1

Answer:

Lithium diisopropylamide [(CH3)2CH]2NLi.

Explanation:

Lithium diisopropylamide (commonly abbreviated LDA) is a chemical compound with the molecular formula [(CH3)2CH]2NLi. It is used as a strong base and has been widely accepted due to its good solubility in non-polar organic solvents and non-nucleophilic nature. It is a colorless solid, but is usually generated and observed only in solution. It was first prepared by Hamell and Levine in 1950 along with several other hindered lithium diorganylamides to effect the deprotonation of esters at the α position without attack of the carbonyl group.