In contrast to hypokinetic diseases, hyperkinetic disorders appear to be associated with abnormally low basal ganglia output from GPi and SNr. Reduced basal ganglia output may arise from a shift of the balance of activity between direct and indirect pathway activity toward the direct pathway.so sedentary living cost our 150 billion ever year , kinetic health problems caused by to much (physical activity)
This is classified by OSHA as a Safety Hazard
