Question

The pediatric oral dose of ciprofloxacin is given as 10 to 20 mg/kg every 8 hours, not to exceed a single dose of 400 mg irrespective of body weight. If a child weighing 55 lb. is prescribed a one-teaspoonful dose of 5% ciprofloxacin oral suspension every 8 hours, calculate whether or not the dose prescribed is within the therapeutic range. Your answer should be "Yes" or "No".

Answer 1

Answer:

No. 5% of ciprofloxacin oral suspension for this child exceeds the therapeutic range.

Explanation:

Single dose of ciprofloxacin suspension shall be 400 mg

the pediatric oral dose is 10-20 mg/kg and body weight of child is 55 lb.

1 kg is 2.2 lb= 55÷ 2.2 = 25 kg

minimum required dose for child is 25 × 10= 250 mg

maximum required dose for child is 25 × 20 = 500 mg

1 teaspoonful is 5000 mg.

500 mg ÷ 5000 mg = 0.1 tsp

Hence, the dose exceeds the therapeutic range.