Answer:
In the third step of the citric acid cycle, the oxidation of isocitrate takes place and one molecule of carbon dioxide is released.
Explanation:
In the first step of citric acid cycle, acetylCoA combines with a four-carbon molecule, oxaloacetate, forming a six-carbon molecule, citrate.
In the second step, the citrate in the presence of enzyme anicotase is converted into isocitrate.
<u>In the third step, the oxidation of isocitrate takes place and one molecule of carbon dioxide is released leaving behind one five-carbon molecule called as α-ketoglutarate. During this step, NAD⁺ is reduced to form NADH. </u>
<u>This is first round of the citric acid cycle that could possibly release a carbon atom originating from this acetyl CoA.</u>
On series of reaction, another carbon dioxide molecule also being relased and oxaloacetate is regenerated again.
