Question

The photos shown below illustrate a case of synpolydactyly, a genetic abnormality characterized by two phenotypes: partially or completely duplicated fingers or toes, and webbing between fingers or toes. The same mutations that give rise to the human phenotype also give rise to a similar phenotype in mice. In which family of genes do you think these mutations occur?

Answer 1

Answer:

Hox gene complex is the set of genes responsible for maintaining the basic body plan of an organism. Synpolydactyly syndrome was the first disorder discovered in human beings that resulted from the mutation in the Hox gene complex. As a result of mutations in the Hox gene complex, syndactyly is inherited, which results in the fusion of fourth and fifth toes and third and fourth fingers.

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