Enzymes are catalysts, meaning stuffs in charge of increasing the rate of chemical or biochemical reactions, they do it so by lowering the energy needed to start chemical reactions, this energy is called <em>"activation energy"</em>; Thereby the best suitable answer is the last one (<em>4th</em>).
The first step of aerobic cellular respiration to evolve is
glycolysis, the evidence that there is to support this is with through the
cytosol of the cytoplasm in which this stage takes place as this is the process
where glucose has been split in two molecules by the enzymes.
The papillary layer provides the layer above it, the epidermis, with nutrients to produce skin cells called keratinocytes. It also helps regulate the temperature of our skin and thus the body as a whole