What is the percentage of a weak acid (pKa = 5.4) in the non-ionized form in plasma (pH 7.4)?
1 answer:
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Answer:
The glycosylation reaction or glycoside formation is an organic reaction in which the hemiacetal group of cyclists ketoses or aldoses turns into acetals, named glycosides. Reaction in the attached picture.
Explanation:
Carbohydrates can be found in an open-chain form or a cyclic form. For the second one, the carbonyl group of the aldehyde could react with the alcohol group of the molecule to form the cycle. As shown in the attached picture, the alcohol group of this cyclic form could react with an alcohol (like methanol) in acidic conditions to form an acetal. These compounds are stable at neutral and acidic conditions, but they hydrolyze at basic conditions. This reaction produces both acetals anomers (α and β) because the attack of the nucleophile (alcohol) could be from both sides. However, the most stable anomer will predominate.
