The timing will depends on the type of drugs the patient had
It should be written on the bottle or the label and the patient just have to follow them.
Some medications will tell you that "Take 1 Capsule in the morning and 1 apsule before bed time"
Other type of medication may tell you that "take 1 - 2 tablets as needed for pain" , that mean that you could only take that if you feel any pain, no prefixed schedule necessary
Medullary sinuses contain histiocytes (immobile macrophages) and reticular cells. A lymph node contains lymphoid tissue, i.e., a meshwork or fibers called reticulum with white blood cells enmeshed in it. The regions where there are few cells within the meshwork are known as lymph sinus.