First pass metabolism of a drug is said to occur when the concentration of a drug that is administered orally is significantly reduced before it reaches the systemic circulation.
First pass metabolism usually occur in the liver.
The routes of drug administration that avoid complete first pass metabolism are: sublingual, transdermal, rectal and inhalation.
They are related because they are all in the same blood or family you breathe in oxygen and remove carbon dioxide the carbon dioxide it helps other stuff in the ecosystem to survive or live so its like this people breathe oxygen while plants breathe carbon dioxide.
Like, evolution as in nothing exploded creating everything? i can DISPROVE evolution with that.
What the larva and pupa stages have in common is that both stages take place in water.
This is where the insect evolves until it becomes fully grown and then leaves water.