Question

Why ph changes disrupt protein's ionic bonds?

Answer 1

Answer:

A change in pH in the protein habitat can modify its ionic bonds because because the chemical equilibrium shifts to one side or the other depends on the modification

Explanation:

The pH influences the charge acquired by the acidic and basic groups present in the molecules. Proteins usually have groups with characteristics of acid or weak base. Therefore, they are partially ionized in solution coexisting in equilibrium different species.

The degree of ionization of the different functional groups is in relation to the pH of the medium in which they are found, since the H3O + and OH- species are part of the equilibrium situation. Therefore, according to the pH, each group with characteristics of weak acid or base present in the molecule will be ionized to a lesser or greater extent. There are extreme situations where the balance has been totally displaced in one direction, for example: under very high pH conditions (low concentration of H3O +) weak acids are considered fully ionized, so the functional group will always have an electric charge. The same goes for the bases at very low pH values. In other equilibrium situations, species of the same molecule with different load will coexist in the solution, due to the pH value of the medium in which it is found.