The IgE antibodies bind to mast cells. The allergen cross-links them. This triggers the mast cells to release powerful chemicals like histamines. Histamines cause the allergic symptoms like itching and runny nose. If you are allergic to pollen, your body will produce a large amount of allergen-specific IgE antibodies when you come in contact with pollen. The IgE antibodies bind to mast cells. The allergen cross-links them. This triggers the mast cells to release powerful chemicals like histamines.
Allergies occur when your immune system reacts to a foreign substance — such as pollen, bee venom or pet dander — or a food that doesn't cause a reaction in most people.
Your immune system produces substances known as antibodies. When you have allergies, your immune system makes antibodies that identify a particular allergen as harmful, even though it isn't. When you come into contact with the allergen, your immune system's reaction can inflame your skin, sinuses, airways or digestive system.
