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Soloha48 [4]
3 years ago
9

This illustration shows a strand of mRNA and the complimentary tRNA molecules that can base pair with the mRNA codons. What is t

he correct sequence of amino acids?
Biology
1 answer:
konstantin123 [22]3 years ago
3 0

Answer:

Since you haven't attached the illustration for finding out the amino acid sequence from the mRNA sequence from, I'll explain the general principle for it.

The mRNA represents the code for translation into specific amino acids which will form the protein. A group of three bases, a triplet code, is referred to as a codon. The tRNA is responsible for recognizing the codon and matching the anticodon that will attach to the mRNA and generate the chain of appropriate amino acids.

Hope that answers the question, have a great day!

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1. The difference between the normal hemoglobin protein DNA sequence and the sickle cell hemoglobin DNA sequence is a base to base shift, in this case adenine (GAG) to thymine (GTG).

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<u>Normal hemoglobin protein in a RBC</u>

DNA                 CTG ACT CCT GAG GAG AAG TCT

Amino acids     Leu  Thr   Pro   Glu   Glu   Lys   Ser

<u>Sickle cell hemoglobin protein in a RBC</u>

DNA                 CTG ACT CCT <em>GTG</em> GAG AAG TCT

Amino acids     Leu  Thr   Pro   <em>Val</em>   Glu   Lys   Ser

When GAG is transcribed to mRNA, the CUC codon is obtained, which codes for glutamic acid. Thymine substitution causes the DNA sequence to change to GTG, which is transcribed as CAC, the codon that encodes the amino acid valine. The <u>change from glutamic acid to valine in β-globin causes an altered hemoglobin, giving the abnormal erythrocytes observed in sickle cell disease</u>.

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