I would say lung cancer. Smoking affects ur lungs the most
The structure that forms cranial nerve I is the olfactory nerves while forming the 2nd is the optic nerve. Together with retina and olfactory epithelium, all of them are considered part of the Central Nervous System — wherein they synapse directly to the brain without the aid of any ganglia.
Up your daily calorie intake by 300 to 350 calories per day — that's the equivalent of, say, two glasses of skim milk and a bowl of oatmeal (not the all-you-can-eat sundae bar you were envisioning).