When a DNA sequence alteration results in a stop codon rather than a codon that specifies an amino acid, it is known as a nonsense mutation. This is rarely seen in 10% of patients with genetic disease.
<h3>What is nonsense mutation?</h3>
A nonsense mutation in a DNA sequence causes a premature stop codon, also known as a nonsense codon, in the transcribed mRNA as well as a shortened, ineffective, and typically nonfunctional protein product.
Because stop codons, also known as nonsense codons, signal the completion of protein synthesis rather than encoding for an amino acid, they are the source of the term "nonsense mutation."
Examples of illnesses for which nonsense mutations have been implicated as contributing factors include: Cystic fibrosis (produced by the G542X mutation in the cystic fibrosis transmembrane conductance regulator); (CFTR) Beta-globin (thalassemia) Hurler disease.
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Well,
By the word "deletion" we can deduce that information is lost. Therefore, when a chromosome undergoes a deletion mutation, information is lost. This can have disastrous effects if it is a human chromosome.
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AMPHIBIAN
Answer:
DNA can be described as the molecules which carries the genetic code for every individual. The DNA is made up of nucleotide bases which join the two strands of DNA. The sugar and phosphate form the backbone of the DNA.
Genes are the hereditary molecules which are made up of DNA. The alleles of a gene represent which traits will be carried by an organism.
Chromosomes are made up of genes. During reproduction, crossing over of DNA occurs and alleles of the genes assort independently due to which variations occur.
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