Answer:
Four possible isomers (1–4) for the natural product essramycin. The structure of compound 1 was attributed to essramycin by 1H NMR, 13C NMR, HMBC, HRMS, and IR experiments.
Explanation:
Three synthetic routes were used to prepare all four compounds (Figure 2A). All three reactions utilize 2-(5-amino-4H-1,2,4-triazol-3-yl)-1-phenylethanone (5) as the precursor, whereas each uses different esters (6–8) to construct the pyrimidinone ring. Isomer 1 was prepared by reaction A, which used triazole 5 and ethyl acetoacetate (6) in acetic acid. This was the reaction used in syntheses of essramycin by the Cooper and Moody laboratories.3,4 Reaction B produced compound 2 (minor product) and compound 3 (major product), which were separated chromatographically. This reaction allowed reagent 5 to react with ethyl 3-ethoxy-2-butenoate (7) in the presence of sodium in methanol, under reflux for 24 h. Compound 4 was prepared by reaction C, which was obtained by reflux of 5 and methyl 2-butynoate (8) in n-butanol.
Arrhenius' Law relates activation energy, Ea, rate constant, K, and temperature, T as per this equation:
K (T) = A * e ^ (-Ea / RT), where R is the universal constant of gases and A is a constant which accounts for collision frequency..
Then you can find the ration between K's at two different temperatures as:
K1 = A * e ^ (-Ea / RT1)
K2 = A* e ^(-Ea / RT2)
=> K1 / K2 = e ^ { (-Ea / RT1) - Ea / RT2) }
=> K1 / K2 = e ^ {(-Ea/ R ) *( 1 / T1 - 1 T2) }
=> K1 / K2 = e^ { (-205,000 j/mol / 8.314 j/mol*k )* ( 1 / 505K - 1/ 485K) }
=> K1 / K2 = e ^ (2.0134494) ≈ 7.5
Answer: 7.5
Nuclear power plants heat water to produce steam. The steam is used to spin large turbines that generate electricity. ... In nuclear fission, atoms are split apart to form smaller atoms, releasing energy. Fission takes place inside the reactor of a nuclear power plant.
It became the model for the Chicago income and property tax program. He used this plan to avoid prosecution for the Chicago fire. This contest-winning design opened Chicago streets to new forms of transportation.
I believe it's better for it to be more abundant because it's better to have more then less. Take water as an example. Water is an important factor to our survival and if we didn't have enough of that we would be in trouble. Or if we needed food but there wasn't enough more people would be dying from starvation. It's better to have a little more than a little less.
