Answer:
As it is a legal abortion she is legally bound to assist. Ethically if her religion or culture prohibit her from completing the task at hand, she will have to take it up with her supervisor or doctor running the procedure.
Explanation:
Answer: Clinical Trials Phase III
Explanation: In order to check if a drug will work and what side effects the drug might have it has to be tested on test subjects so they can document everything that may happen.
Answer:
Macromolecules are transported from one space to another through a process of transcytosis or transcellular transport. It consists of a series of steps that will allow the mobility of macromolecules from one extracellular space to another, through the cellular menbrain, through a vesicle formation process. These vesicles maintain a certain load inside. The processes that are generated for the transcytosis process are those of endocytosis and exocytosis.
Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
Explanation:
a growing population, aging seniors, disease prevalence or incidence, medical service utilization, and service price and intensity.
