When insulin is deficient , GLUT4 transporters are not inserted into the cell membranes , glucose is not transported into the cells and the blood glucose concentration increases.
Insulin deficiency provides more amino acid and glycerol substrates for glucose synthesis ie increased gluconeogenesis .
With a deficiency of insulin, there is both increased hepatic glucose production through increased glycogenolysis and gluconeogenesis as well as decreased glucose use. The result is hyperglycemia.
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Answer: Option b
Explanation:In chemistry,
before any reaction would occurs, reactat must be able to overcome some certain amount of energy which is called the activation. The activation energy is usually the heat that is suppled.it is also refered to as the minimum energy needed before any reaction can take place. For reaction to take place, there must be an equilibrium( at constant temperature and pressure.