A 2-month-old is diagnosed with Hirschsprung disease with the resulting development of a megacolon. <u>absence of intrinsic </u><u>ganglion cells</u><u> resulting in impaired peristalsis</u><u> </u>is the most likely cause of this condition.
The vertebrate retina's ganglion cells are the last neurons to leave the cell. In the retinal wiring design, the ganglion cell gathers the electrical messages pertaining to the visual signal from the two layers of nerve cells that come before it. All common excitatory or inhibitory retinal neurotransmitters are reacted with by ganglion cells.
The retina's deepest layer, which is closest to the lens and front of the eye, contains ganglion cells. The elements of the visual world are extracted by ganglion cells, encoded in frequency-modulated spike trains, and sent coursing along the axons of the optic nerve to various visual brain areas.
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