The big bang theory states that the universe began approximately 10-20 billion years ago in an expansion of the universe emanating from an extremely compact point. The occurrence of super massive black holes contradict the big bang theory. Super massive black holes are found at the center of galaxies and is what keeps them together. Models do not explain how these would have formed if the big bang occurred the way it was proposed.
NADPH, or nicotinamide adenine dinucleotide phosphate, is essential for photosynthetic organism carbohydrates. This reduced coenzyme is a high energy molecule and a reduced form of NADP+ that plays a key role in driving the Calvin cycle.