Answer:
The post-transcriptional modifications in the mRNA produced as a result of the transcription in eukaryotes provide many advantages to the mRNA.
The two post-transcriptional modifications are the addition of 7-methylguanosine cap at 5' end of mRNA called capping whereas the addition of the poly(Adenyl) tail at 3' end called tailing.
The advantages of capping are:
1. Protection of nascent mRNA from the degradation.
2. Recognition by transcription factors helps in translation.
The advantages of tailing are:
1. Protection of the mRNA from enzymatic degradation in the cytosol.
2. Transcription termination
3. Export of the mRNA from the nucleus
Tretinoin is a naturally occurring metabolite of retinol in the retinoid class, including natural and synthetic analogues. It is the acid form of vitamin AIt acts on cell growth and differentiation. Its main use is the treatment against acne thanks to its keratolytic and anti-inflammatory properties. Tretinoin is also used in the treatment of acute myeloid leukaemia type 3 (AML 3).
SIDE EFFECTS:
Among the expected effects, side effects may occur. Signs of an allergic reaction include: hives, difficulty breathing, swelling of the face, lips, tongue or throat;
It should be known that tretinoin can make you more sensitive to the sun, so use sunscreen every day, and wear protective clothing outdoors.
Cholesterol and triglycerides should be done before and during treatment because this drug could increase their values
Some patient with leukaemia treated by tretinoin has suffered from The syndrome of retinoic acid which is characterized by fever, dyspnea, acute respiratory distress...
The term that best completes the given statement above is the word ATTENUATED. A method of producing an attenuated vaccine is through genetic manipulation of a microbe to remove one or more virulence factors. The purpose of creating attenuated vaccines is to reduce the effect of a microorganism to the body. Once the body is exposed to the said disease, it will not experience a dreadful effect done by the microorganism.
Answer: Ectotherms depend on external heat sources. Their body temperature changes with the temperature of the environment. Endotherms generated heat internally to maintain body temperature.
Explanation:
