1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
Sedaia [141]
3 years ago
13

how to determine the net charge of the tripeptide Asp-Gly-Leu at pH 7. Can someone show in details and tricks on how to solve it

? Thank you!!
Chemistry
1 answer:
Ugo [173]3 years ago
5 0

Answer:

0!

Explanation:

  • You need to search your pKa values for Asn (2.14, 8.75), Gly (2.35, 9.78) and Leu(2.33, 9.74), the first value corresponding to -COOH, the second to -NH3 (a third value would correspond to an R group, but in this case that does not apply), and we'll build a table to find the charges for your possible dissociated groups at indicated pH (7), we need to remember that having a pKa lower than the pH will give us a negative charge, having a pKa bigger than pH will give us a positive charge:            

           

                   -COOH         -NH3              

pH 7------------------------------------------------------              

Asn               -                      +

Gly                -                      +

Leu               -                      +

  • Now that we have our table we'll sketch our peptide's structure:

<em>HN-Asn-Gly-Leu-COOH</em>

This will allow us to see what groups will be free to react to the pH's value, and which groups are not reacting to pH because are forming the bond between amino acids. In this particular example only -NH group in Ans and -COOH in Leu are exposed to pH, we'll look for these charges in the table and add them to find the net charge:

+1 (HN-Asn)

-1 (Leu-COOH)

=0

The net charge is 0!

I hope you find this information useful and interesting! Good luck!

You might be interested in
Conservation of matter article questions
elena-14-01-66 [18.8K]

The Law of conservation of mass states that  option C: matter is neither created nor destroyed.

<h3>What is the law of conservation of matter?</h3>

Physical and chemical changes can cause matter to transform into different forms, but no matter what happens, matter is always conserved. There is no creation or destruction of matter; the amount of matter is the same before and after the transformation.

The principle of matter conservation. argues that matter cannot be generated or destroyed during a chemical reaction. The same number of atoms exist before and after the alterations even though the matter may shift from one form to another. reactant.

Therefore, According to the principle of mass conservation, neither chemical processes nor physical changes can create or destroy mass in an isolated system. The mass of the products and reactants of a chemical reaction must be equal, in accordance with the law of conservation of mass.

Learn more about matter from

brainly.com/question/3998772
#SPJ1

See full question below

1. Multiple-choice

Q.

Conservation of matter article questions

Law of conservation of mass states that

answer choices

matter is created

matter is destroyed

matter is neither created nor destroyed

matter does not change

3 0
1 year ago
The element nickel has the following properties. Select the two that are chemical properties of nickel.
kkurt [141]
<span>a. It melts at 1455oC I know this is correct I need One more</span>
5 0
3 years ago
How are hail and snow similar?
Debora [2.8K]

Answer:

the answer is a

Explanation:

i did process of elimination and i got a

3 0
2 years ago
For dessert, she prepares to bake a delicious apple pie. During one of the steps, she
Leno4ka [110]

Answer:

heating the sugar

Explanation:

6 0
3 years ago
Read 2 more answers
5.4 When looking down the C{{TOP-HAT-MATH-TOKEN-0}}-C{{TOP-HAT-MATH-TOKEN-1}} bond in 2,3-dimethylbutane, what is the most stabl
AURORKA [14]

Answer:

The most stable conformer would be the anti-conformer when the substituent methyl groups are farthest away from each other.

Explanation:

Isomers are chemical compounds with the same molecular formula but with different molecular structures.

Conformers are a special type of isomers that produce different structures when the substituents of a Carbon-Carbon single bond (C-C) are rotated.

In 2,3 dimethyl butane, the substituent methyl groups are located around the second and third Carbon to Carbon single bond.

To achieve a stable configuration, the methyl group substituents need to be as far apart as possible (that is, in an anti-position) to minimise repulsion.

The closer the methyl groups are to each other, the more they repel each other and the more unstable the conformer becomes.

7 0
3 years ago
Other questions:
  • Which elements have fewer than four dots in their electron dot diagrams
    8·2 answers
  • A balanced chemical equation used to prepare ammonium carbonate, (nh4)2co3 , is: 2 n h 3 ( g ) + c o 2 ( g ) + h 2 o ( l ) ⟶ ( n
    9·1 answer
  • How do ionic bonds affect the properties of ionic compounds
    14·1 answer
  • Which of the following statements about atoms is NOT true?
    7·1 answer
  • Phagocytic cells perform their function by
    12·1 answer
  • Number of valence electrons for nitrogen
    7·1 answer
  • A solution of nitric acid has a [H3O+] = 2.8 x 10-6 M. What is the pH?
    15·1 answer
  • 19 Down syndrome is a genetic disorder caused by the
    6·1 answer
  • HELP HELP HELP!! Explain the various factors that impact the solubility of substances in water.
    6·2 answers
  • 50 POINTS for a legitimate response. Please answer the question, chose the correct unit conversions on the right. Please read th
    6·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!