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Sedaia [141]
3 years ago
13

how to determine the net charge of the tripeptide Asp-Gly-Leu at pH 7. Can someone show in details and tricks on how to solve it

? Thank you!!
Chemistry
1 answer:
Ugo [173]3 years ago
5 0

Answer:

0!

Explanation:

  • You need to search your pKa values for Asn (2.14, 8.75), Gly (2.35, 9.78) and Leu(2.33, 9.74), the first value corresponding to -COOH, the second to -NH3 (a third value would correspond to an R group, but in this case that does not apply), and we'll build a table to find the charges for your possible dissociated groups at indicated pH (7), we need to remember that having a pKa lower than the pH will give us a negative charge, having a pKa bigger than pH will give us a positive charge:            

           

                   -COOH         -NH3              

pH 7------------------------------------------------------              

Asn               -                      +

Gly                -                      +

Leu               -                      +

  • Now that we have our table we'll sketch our peptide's structure:

<em>HN-Asn-Gly-Leu-COOH</em>

This will allow us to see what groups will be free to react to the pH's value, and which groups are not reacting to pH because are forming the bond between amino acids. In this particular example only -NH group in Ans and -COOH in Leu are exposed to pH, we'll look for these charges in the table and add them to find the net charge:

+1 (HN-Asn)

-1 (Leu-COOH)

=0

The net charge is 0!

I hope you find this information useful and interesting! Good luck!

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Aqueous concentrated nitric acid is 69% hno3 by weight and has a density of 1.42 g/ml.
OleMash [197]

Answer: -

15.55 M

35.325 molal

Explanation: -

Let the volume of the solution be 1000 mL.

Density of nitric acid = 1.42 g/ mL

Total Mass of nitric acid Solution = Volume of nitric acid x Density of nitric acid

= 1000 mL x 1.42 g/ mL

= 1420 g.

Percentage of HNO₃ = 69%

Amount of HNO₃ = \frac{69} {100} x 1420 g

= 979.8 g

Molar mass of HNO₃ = 1 x 1 + 14 x 1 + 16 x 3 = 63 g /mol

Number of moles of HNO₃ = \frac{979.8 g}{63 g/ mol}

= 15.55 mol

Molarity is defined as number of moles per 1000 mL

We had taken 1000 mL as volume and found it to contain 15.55 moles.

Molarity of HNO₃ = 15.55 M

Mass of water = Total mass of nitric acid solution - mass of nitric acid

= 1420 - 979.8

= 440.2 g

So we see that 440.2 g of water contains 15.55 moles of HNO₃

Molality is defined as number of moles of HNO₃ present per 1000 g of water.

Molality of HNO₃ = \frac{15.55 x 1000}{440.2}

= 35.325 molal

3 0
3 years ago
The edge length of the unit cell of KCl (NaCl-like structure, FCC) is 6.28 Å. Assuming anion-cation contact along the cell edge,
Mila [183]

Answer:

1.33 Å

Explanation:

Given that the edge length , a of the KCl which forms the FCC lattice = 6.28 Å

Also,

For the FCC lattice in which the anion-cation contact along the cell edge , the ratio of the radius of the cation to that of anion is 0.731.

Thus,

\frac {r^+}{r^-}=0.731 .................1

Also, the sum of the radius of the cation and the anion in FCC is equal to half of the edge length.

Thus,

r^++r^-=\frac {a}{2}  ...................2

Given that:

Cl^-\ (r^-) = 1.82\ \dot{A}

To find,

K^+\ (r^+) = ? \dot{A}

Using 1 and 2 , we get:

1.731\ r^+=0.731\times \frac {6.28}{2}

<u>Size of the potassium ion = 1.33 Å</u>

4 0
3 years ago
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