Imatinib is a small molecule kinase inhibitor. The BCR-ABL kinase can phosphorylate a series of downstream substrates, leading to proliferation of mature granulocytes. Bcr-Abl kinase substrate is the tyrosine. The Protein Tyrosine Kinase activity is an important requirement for malignant transformation, and that it cannot be complemented by any downstream effector, though not all interactions of BCR-ABL with other proteins are phosphotyrosine dependent.
Oxidation reaction.
Cathode on the other hand is reduction.
<h3><u>Answer;</u></h3>
A) HNO3 and NO3^-
<h3><u>Explanation;</u></h3>
- <em><u>HNO3 is a strong acid and NO3 is its conjugate base, meaning it will not have any tendency to withdraw H+ from solution.</u></em>
- Buffers are often prepared by mixing a weak acid or base with a salt of that weak acid or base.
- The buffers resist changes in pH since they contain acids to neutralize OH- and a base to neutralize H+. Acid and base can not consume each other in neutralization reaction.
