DNA is condensed by a certain amount just on its own, just by its own interactions within the DNA molecule,..but whne proteins get involved it gets condensed 30000 fold
<span>what happens is that proteins called histones are like hockey pucks, and DNA wraps around it 1.5 times and then goes to another histone and wraps around that so that it looks like beads on a string (i hope that makes sense, its the only way to describe it) </span>
<span>these histones condense this DNA a lot, and when the histones get methylated then the DNA packs together even closer to get heterochromatin (VERY densely packed DNA)...the theory here is that DNA has a net negative charge due to the phosphate groups in the DNA backbone and doesnt allow the DNA to come together as closely as it could (like charges repel like charges), but when histones are methylated, the negative charge on the DNA is masked by the methyl groups and DNA can come together closer </span>
Answer:
Citrate Synthase facilitates the formation of citrate by deprotonating Acetyl CoA and by protonating the carbonyl oxygen of oxaloacetate
Explanation:
Citrate synthase is a key enzyme in the citric acid cycle that functions to catalyze the formation of citrate from oxaloacetate and acetyl-CoA: acetyl-CoA + oxaloacetate + H2O >> citrate + CoA-SH (Coenzyme A ). This enzyme contains three amino acids at its active site that work together to catalyze the conversion of acetyl-CoA and oxaloacetate into citrate. This active site acts by abstracting (deprotonating) a proton from the alpha carbon of Acetyl CoA which serves as the nucleophile. Subsequently, the active site of the enzyme also protonates the carbonyl oxygen of oxaloacetate, which then suffers nucleophilic attack and thereby facilitating nucleophilic substitution reaction.
Answer:
Endocrine and Cardiovascular system
Explanation:
Excess fat intake leads to different health hazards. They affect the body and cause lipids to clog the arteries thereby preventing blood from quickly delivering oxygen to the body parts.
Excess fat intake causes fatty pancreas and decreases its function.
It also causes series of cardiovascular diseases such as heart attack; elevated cholesterol/atherosclerosis,abnormal heart rhythms, hypertension, stroke etc
