Answer:
Ant sting release methanoic acid or formic acid. The chemical formula of methanoic acid is HCOOH
Number 6 is add up all the numbers, then divide by how many numbers there are. In other words it is the sum divided by the count.
7. You should use a line graph when your need to track changes over short and long periods of time
8. The dependent variable goes on the y axis
Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
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The clavicle or the collar bones are the only long bones in the body that lie horizontally. Calling the clavicle as the beauty bone is basedon the reason that it helps frame the face and round out the imperfection of your jaw line.
Answer:
Sunlight is important in my life because you need it if you have a plant and you want to take care of the plant.Postive effects of sunlight is Sun water and needing health
