Answer:
A change in pH in the protein habitat can modify its ionic bonds because because the chemical equilibrium shifts to one side or the other depends on the modification
Explanation:
The pH influences the charge acquired by the acidic and basic groups present in the molecules. Proteins usually have groups with characteristics of acid or weak base. Therefore, they are partially ionized in solution coexisting in equilibrium different species.
The degree of ionization of the different functional groups is in relation to the pH of the medium in which they are found, since the H3O + and OH- species are part of the equilibrium situation. Therefore, according to the pH, each group with characteristics of weak acid or base present in the molecule will be ionized to a lesser or greater extent. There are extreme situations where the balance has been totally displaced in one direction, for example: under very high pH conditions (low concentration of H3O +) weak acids are considered fully ionized, so the functional group will always have an electric charge. The same goes for the bases at very low pH values. In other equilibrium situations, species of the same molecule with different load will coexist in the solution, due to the pH value of the medium in which it is found.
<span>Fungal diseases are difficult to treat mainly because they are eukaryotic organisms just like us humans, and therefore have less differences for drugs to target without harming the human body as well. Most antibiotics target e.g. the peptidoglycan layer in the bacterial (a prokaryote) cell wall, which is a safe target since eukaryotic cells do not have equivalent structures. Similarly many differences in metabolic pathways between humans and prokaryotes is often targeted by antibiotics, but metabolism of fungi and humans is much more uniform, and hence it is difficult to exclusively target the fungi only.
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Mass of methanol (CH3OH) = 1.922 g
Change in Temperature (t) = 4.20°C
Heat capacity of the bomb plus water = 10.4 KJ/oC
The heat absorbed by the bomb and water is equal to the product of the heat capacity and the temperature change.
Let’s assume that no heat is lost to the surroundings. First, let’s calculate the heat changes in the calorimeter. This is calculated using the formula shown below:
qcal = Ccalt
Where, qcal = heat of reaction
Ccal = heat capacity of calorimeter
t = change in temperature of the sample
Now, let’s calculate qcal:
qcal = (10.4 kJ/°C)(4.20°C)
= 43.68 kJ
Always qsys = qcal + qrxn = 0,
qrxn = -43.68 kJ
The heat change of the reaction is - 43.68 kJ which is the heat released by the combustion of 1.922 g of CH3OH. Therefore, the conversion factor is: