Evidence suggests that cAMP response-element-binding protein (CREB) may be a final common target of antidepressant treatment.
Antidepressant medications work by binding to a number of monoamine neurotransmitter receptors and activating the cAMP signal transduction pathway. Chronic antidepressant therapy has been linked to the cAMP signalling system. Increases in cAMP cause the cAMP response element-binding protein(CREB) to be phosphorylated more frequently via increased receptor adenylate cyclase activity .
CREB mediates transcriptional responses to increased cAMP levels by attaching to cAMP response element (CRE) sites.In order to prevent recurring episodes, treatment for depression should maintain therapeutic efficacy while also addressing behavioural symptoms and indicators of the illness. One important modulator of the transcriptional effects of antidepressants may be CREB.
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Because the heart is forced to pump out blood. In the upper right side of the heart is an bundle of cells called the sinoatrial node. Unlike any other cell in the body, these cells (nicknamed "pacemakers") keep sending out electrical impulses, more than once a second, to make the rest of the heart contract and pump out blood.
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Answer:
I would choose to stay home even if I wanted to go.
Explanation:
If you value the sport then you shouldn't risk getting hurt.
The purpose of learning the medication dosages is that the wrong dosage can lead to a overdose which leads to death or other side effects
Answer:
B
Explanation:
skipping meals can be a bad influence on your health as it drives off the routine you are used to. causing vomiting, loss of weight, and an unhealthy image of what you are doing is right.