Question

Which scenario supports the ""one gene–one enzyme"" hypothesis of metabolic disease causation?

Answer 1

The scenario that supports the "one gene-one enzyme" hypothesis of metabolic disease causation is Phenylketonuria (PKU). This disease (PKU) is caused by the failure to produce a functional variant of an enzyme.

Phenylketonuria (PKU) is a metabolic inherited disorder associated with a decreased metabolism of the amino acid phenylalanine.

PKU is caused by a mutation in the gene responsible for encoding a key enzyme needed to break down phenylalanine.

Untreated PKU may lead to diverse health problems which include brain damage, intellectual disability, seizures, mental disorders, etc.

Learn more in:

brainly.com/question/7157066?referrer=searchResults