What grade are you in if you are in 5th or 6th i can help you
        
             
        
        
        
<h3><u>Answer;</u></h3>
b). Activation of an upstream guanine nucleotide exchange factor
<h3><u>Explanation</u>;</h3>
- <em><u>When a ligand activates the G protein-coupled receptor, it induces a conformational change in the receptor that allows the receptor to function as a guanine nucleotide exchange factor (GEF) that exchanges GDP for GTPthus turning the G protein-coupled receptor on.</u></em>
- The activated G-protein then dissociates into an alpha (G-alpha) and a beta-gamma complex. 
 
        
        
        
Answer:
This question is asking to identify the directional relationship between the following organs. They are explained below. 
Explanation:
1. The heart is MEDIAL to the lungs because it is located towards the middle in relation to the right and left lungs. 
2. The knee is DISTAL to the hip because it is farther away from the point of attachment of the hip joint.
3. The wrist is PROXIMAL to the hand because the wrist is closest to the point of origin of the hand.
4. The mouth is INFERIOR to the nose because it is lower in direction to the nose.
5. The thorax is SUPERIOR to the abdomen because it is located above the abdomen. 
6. The thumb is DISTAL to the ring finger because it is far away from the ring finger.
7. The sternum is ANTERIOR to the heart because it lies in front of the heart 
8. The skull is SUPERFICIAL to the scalp because it is close to the body surface. 
9. The ears are LATERAL to the nose because it is towards the middle line of the nose
10. Dorsal refers to the BACK of the human body, while ventral refers to the FRONT of the human body.
 
        
             
        
        
        
Enzyme speed up chemical reaction by lowering activation rates