A class of lipids called prostaglandins is typically produced at the sites of injury or infection and is used to treat both disease and injury. They regulate functions like blood flow, blood clot formation, inflammation, as well as labor induction.
Arachidonic acid, from whom prostaglandins are generated, is what causes inflammation:
- In synthetic form, prostaglandins are used to induce labor and give birth.
- They trigger uterine contractions and have a ring structure with at least two or three and perhaps more carbons.
Effects of prostaglandins in the body are
- The hormone that circulates and regulates the kidney's reabsorption of sodium. Prostaglandins, which seem to be present in high concentrations, directly affect nerve terminals to induce pain.
- The production of the inflammatory response is significantly influenced by prostaglandins. Their production is markedly increased in inflamed tissue, therefore they help to produce the essential symptoms of acute inflammation.
- NSAIDs (which inhibit cyclooxygenase) as well as COX-2 selective inhibitors, sometimes known as coxibs, were examples of prostaglandin antagonists. Cyclopentenone prostaglandins as well as corticosteroids, which block the formation of phospholipase A2, might help to reduce inflammation.
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