Question

6. A breed of cattle called the Piedmontese cattle has the same type of extra muscle as the Belgian Blue cattle; however, the mutation to the myostatin gene is different. It is caused by a point mutation that changes a guanine to an adenine at DNA nucleotide number 941. This causes cysteine to be replaced with tyrosine in the amino acid sequence. Is this a silent mutation, missense mutation, or nonsense mutation

Answer 1

The mutation that occured in the Piedmontese cattle is a missense mutation because there is a change in amino acid.

WHAT IS A MUTATION?

A mutation is any alteration in the nucleotide sequence of the DNA of an organism. Mutation can be of different types depending on how it occurs:

1. Missense mutation
2. Nonsense mutation
3. Silent mutation

A missense mutation is a type of mutation that alters (modifies) the encoded amino acid, thereby changing the resulting protein.

According to this question, the mutation that occured in the cattle changes a guanine to an adenine at DNA nucleotide number 941. This causes cysteine to be replaced with tyrosine in the amino acid sequence.

Therefore, the mutation that occured in the Piedmontese cattle is a missense mutation because there is a change in amino acid.

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Answer 2

It is a missense mutation because this alteration changes the encoded amino acid. This type of mutation may have evolutionary consequences.

What are mutations?

A mutation is any alteration in the nucleotide DNA sequence of the genome of an organism.

A missense mutation is a type of mutation that alters (modifies) the encoded amino acid, thereby changing the resulting protein.

Missense mutations have the potential to alter the function of the resulting protein and therefore they have evolutionary consequences.

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