The normal range of urine output is 800 to 2,000 milliliters per day if there’s a normal fluid intake of about 2 liters per day.
The nurse should ensure that the Naloxone should be readily available.
<h3>What is Naloxone?</h3>
It is frequently used to combat breathing problems brought on by opiate overdose. It is also possible to combine naloxone with an opioid (in the same pill) to reduce the chance of injection usage. When administered intravenously, effects start to take effect after two minutes, and after five minutes if an injection is placed into a muscle. The medication can also be sprayed directly into the nostrils of the patient. For 30 to 90 minutes, naloxone often prevents the effects of opioids. Some opioids have longer half-lives than naloxone, thus multiple doses can be necessary.
When administered to opioid-dependent people, withdrawal symptoms from opioids, such as restlessness, agitation, nausea, vomiting, a rapid heartbeat, and sweating, may occur.
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Answer:
Drug-drug interactions (DDIs) are one of the commonest causes of medication error in developed countries, particularly in the elderly due to poly-therapy, with a prevalence of 20-40%. In particular, poly-therapy increases the complexity of therapeutic management and thereby the risk of clinically important DDIs, which can both induce the development of adverse drug reactions or reduce the clinical efficacy. DDIs can be classify into two main groups: pharmacokinetic and pharmacodynamic. In this review, using Medline, PubMed, Embase, Cochrane library and Reference lists we searched articles published until June 30 2012, and we described the mechanism of pharmacokinetic DDIs focusing the interest on their clinical implications.
Keywords: Absorption, adverse drug reaction, distribution, drug-drug interactions, excretion, metabolism, poly-therapy
