The obsessive disinhibition form of a craving is the result of dysfunction in the<u> </u><u>5ht </u>neurotransmitter.
<h3>5HT neurotransmitter:</h3>
One of the major neurotransmitters in mammals' nervous systems is 5-HT (also known as serotonin), which is well known for modulating key aspects of daily living like mood, sleep, social behaviors, learning, and appetite (Barnes and Sharp, 1999; Gingrich and Hen, 2001; Canli and Lesch, 2007).
The central and peripheral nervous systems contain a variety of G protein-coupled receptors and ligand-gated ion channels known as 5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors. Both excitatory and inhibitory neurotransmission is mediated by them.
5-HT produces only inhibitory effects on excitatory or inhibitory transmission in the bed nucleus of the stria terminalis (BNST) [16] and the periaqueductal grey (PAG).
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