Glycolysis takes place in the cytoplasm, and the Krebs cycle takes place in the mitochondria of the cell.
Glycolysis is an anaerobic process. During glycolysis, partial oxidation of glucose occurs, which produces two molecules of pyruvic acid.
Krebs cycle occurs in the mitochondrial matrix. It is an aerobic process which produces Carbon dioxide after complete oxidation of pyruvic acid that is made up during glycolysis.
The pyruvate formed by the reduction of glucose in the glycolysis is broken down into acetyl-CoA which then enters the Krebs cycle and condenses with oxaloacetate to form citrate. One pyruvate molecules yields 15 ATP and therefore, two pyruvate molecules lead to the production of 30 ATP.
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