I believe it is nephropathy which can lead to kidney failure and death.
It is D, sharing appreciation for what is being said. Both A and B aren't crucial to being a good listener, in fact in practice they effectively draw attention to yourself, which would be fine if the question was regarding being a good conversationalist. Additionally, C is just completely irrelevant, that wouldn't even be a good conversation practice, let alone a trait important to listening.
its the third option, it describes it very accurately.
Today's health challenges are formidable, including an ageing population; unhealthy lifestyles; the burden of behavioural determinants leading to increased mortality and morbidity from noncommunicable diseases; the rapid transfer of infectious pathogens and the potential for global pandemics; national disasters.
The nearest ten thousand is: 760,000