I would have to say being exessively over weight
<span>In a neurophysiological investigation, a monkey makes an involuntary gesture when a portion of its brain is electrically stimulate, the area of the brain that was most likely stimulated is the posterior portion of the frontal lobe. The posterior portion is where the ventral and dorsa of the frontal plane is located. </span>
The drug connects receptors that are only connected during sex, eating your favorite food, excising, etc. Therefore releasing <span>Endorphins. This makes you feel really good. Soon your brain will run out of </span><span>Endorphins since the drug makes it release them all at once making you need the drug to function (addiction).</span>
One example is to run around your neighborhood