* More than 40 proteins and glycoproteins involved in the complement system are synthesized by the liver, macrophages, epithelial cells, they are present in the blood in plasmatic form, membrane, some have an enzymatic activity, regulator or membrane receptorThese are elements of the humoral innate immune response, they fight infections, purify immune complexes and apoptotic bodies.
<span>There are indeed three ways to activate the complement:</span>
Classical pathway: Activated by Immunoglobulins in immune complexes, aggregated Immunoglobulins, DNA, CRP, apoptotic bodies .......it involves nine fractions, starting with C1, then C4, C2, C3, to form a classical C5 convertase, then, activation of C5, C6, C7, C8, C9.
Alternative pathway: activated by polysaccharides (bacterial endotoxin), vascular wall poor in sialic acid, aggregated IgE ...C3b like is the first component in the alternate channel cascade, it will create an amplification loop, and form an alternative C5 convertase.
Lecithin pathway: Activated by mannose, fucose (carbohydrate of microorganisms)The first component is the complex MBL / MASP1 / MASP2: "mannose-binding protein": works according to the same principle as the complex C1 of the classical way (MASP2 cleaves the C4 and the rest of the cascade is equivalent to that of the classical way).
the three ways have the same outcome: A C5 convertase (formed by one of the pathways) cleaves C5 into C5a and C5b: C5b is deposited far from other fractions on the antigenic surface. The fixation of C5b in the cell is followed by that of C6, C7, C8, and C9 (9 molecules of C9): formation of the membrane attack complex (MAC) ==> Death of the cell by osmotic shock
For a 2 year old patient who was severely dyspneic and now unresponsive and no longer breathing, you will instruct your EMT to insert an OPA and begin give positive pressure ventilations with a BVM with 100% O2 to the patient. Palpate for a pulse and if <10 seconds you cannot feel a pulse, you will begin chest compressions.
The good thing about respiratory codes in children is that they normally always code due to lack of oxygenation. Once they are finally re-oxygenated, they will typically come around with better vitals.
Answer:
Binocular vision
Explanation:
Vision can be explained as an ability to see directly some things that can be a threat or of benefits . It can also be explained as the ability to sense or perceive threat or danger, or something good.
In this case, binoculars vision is a situation of sensing threats or dangers from a very distant place through the help of the brain. Most times, the brain will be able to sense dangers from the interpretation it gathered from what it saw earlier, before the person is involved in the act.
Answer:
B. bituminous
Explanation:
Bituminous coal is an organic sedimentary rock produced by compression of peat bog material by diagenesis and submetamorphics.
Bituminous coal has low moisture and high carbon content and hence used for the production of steel and cement, coke production an electricity generation.
Coking coal is a type of Bituminous coal are best used as fuel dource in metal industry having very narrow range of volatility and plasticity. Volatility is maintained by smelters to optimize the ease of burn rate, ignition, and energy output of the coal as this determines the burn rate of the coal.
Hence, the correct option is B. bituminous.
A genus is composed of a number of similar SPECIES.
