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Fantom [35]
3 years ago
6

Can someone explain the process of RNA editing?

Biology
1 answer:
Talja [164]3 years ago
8 0
The process of RNA editing is the alteration of the sequence of nucleotides in the RNA after it has been transcribed from DNA, but before it is translated into a protein. RNA editing occurs by two distinct mechanisms:<em><u /><u>Substitution</u> <u>editing </u></em>and <u><em>Insertion/</em></u><em></em><u><em>deletion</em></u><em> <u>editing</u></em>.

<u><em>Substitution editing</em></u> is the chemical alteration of individual nucleotides. These alterations are catalyzed by enzymes that recognize a specific target sequence of nucleotides:

*Cytidine Deaminases that convert a C in the RNA to uracil.

*<em />adenosine deaminases that convert an A to inosine,which the ribosome translates as a G.<span>Thus a CAG codon</span><span> (for Gln) can be converted to a CGG codon (for Arg).

<em><u>*Insertion/deletion editing</u></em><em><u /></em><u /> is the insertion or deletion of nucleotides in an RNA.

These alterations are mediated by guide RNA molecules that base-pair as best they can with the RNA to be edited and serve as a template for the addition( or removal) in the target.</span>
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