Membrane proteins are not soluble in water solutions. To purify and crystallize membrane proteins, the proteins need to be disso
lved in a solution containing mild detergents such as Beta-octyl-glucopyranoside (see the structure below). Please explain how the detergents solubilize a membrane protein.
Detergents are knows as a class of molecules whose having unique properties to enable formation of hydrophobic-hydrophilic interaction among molecules in membrane. This unique property of detergents are used to dissolve membrane protein in water solution or in any solution.
Detergents are used to lyse cells, solubilize membrane lipids, and proteins, prevent protein crystalization, and nonspecific binding.
Because the red eyes are recessive to black eyes, the parents could be heterozygous. Recessive alleles only show if two recessive alleles are combined. Thus the offsprings phenotypes of the gene would be C. Rr and rr
