The inducible isoform (NOS<span>-2) is calcium-independent and produces large amounts of </span>gas<span> that can be cytotoxic. </span>NOS<span> oxidizes the guanidine group of L-</span><span>arginine in a process that consumes </span>five<span> electrons and results in the formation of NO with stoichiometric formation of L-citrulline. </span>
