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seropon [69]
3 years ago
7

A mutation that results in a single amino acid substitution in Ras abolishes its ability to hydrolyze GTP, even when GTPase-acti

vating proteins (GAPs) are present. Approximately 30% of human cancers have this mutation in Ras. The pharmaceutical company AztraZeneca, which markets popular breast cancer drugs like Iressa® (generic: Gefitinib) has recently developed a new drug that prevents the dimerization of a receptor tyrosine kinase expressed in lung cancer cells, which signals via Ras. Would you expect this new drug to be effective for the treatment of cancers that express the mutant form of Ras?
Biology
1 answer:
Drupady [299]3 years ago
7 0

Answer:

The new drug will not be effective against the treatment of cancer.

Explanation:

The drug will not be effective against the cancer treatment because the drug will inhibit the dimerization of receptor tyrosine kinase (RTK) but as the Ras has undergone mutation due to replacement of one amino acid, it will be constitutively expressed and the drug is not effective in stopping the Ras functioning.

Thus, Gefitinib cannot work against the cancerous cell as it is not potent to stop the functioning of mutant Ras protein.

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Options: A. contralateral

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Explanation:The ciliospinal reflex which is also known bas pupillary-skin reflex is usually made uo of the dilation of the ipsilateral pupil this dilation is in response to pain applied to the neck, face, and upper trunk.

If you stimulate the left side of the subject, the response will be only in the ipsilateral which means the stimulation will be felt in the same side of the subject which in this case is the Left side if the subject.

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4 years ago
What term is defined as mathematical equations based on rules of physics
Svetlanka [38]
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3 years ago
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Stels [109]

Answer:

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3 0
3 years ago
Based on the data, what would likely be the abundance of organisms that perform aerobic cellular respiration at a depth of 1,000
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3 years ago
Explain why it was important to keep on set of seedling in the light​
tiny-mole [99]

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Explanation:

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When root is formed and anchored to the ground a shoot emerges from hypocotyl.

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4 years ago
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