Answer:
The answer is reciprocal chromosomal translocation
Explanation:
The Philadelphia chromosome (Ph) is the truncated chromosome 22 generated by the reciprocal translocation t(9;22)(q34;q11) and was first identified in 1960 in a patient with CML [3]. Translocation of the proto-oncogene tyrosine-protein kinase (ABL1) gene located on chromosome 9 to the breakpoint cluster region (BCR) gene located on chromosome 22 results in a BCR-ABL1 fusion gene on the Ph [4, 5]. Three BCR-ABL1 fusion gene hybrids encode BCR-ABL1 protein isoforms p210, p190, and p230, which have persistently enhanced tyrosine kinase (TK) activity. These aberrantly activated kinases disturb downstream signaling pathways, causing enhanced proliferation, differentiation arrest, and resistance to cell death [6, 7]. Tyrosine kinase inhibitors (TKIs) targeting the BCR-ABL1 protein are the most successful targeted therapy for Ph-positive leukemia.
Answer:
Can you put a gene from a certain species into a different species?
Can you put a gene from one organism into the same organism?
What is a new gene?
Try to stay true to who you are and find a good reason as to why you should be a great leader such as if you are in any AP classes or if you have demonstrated good leadership skills in the past. And if everything else fails people like food so you could bake/cook something cool that's has to do with science. Good luck!
Astronomer Edwin Hubble classified galaxies<span> into four major types: spiral, barred spiral, elliptical and irregular. Most of the nearby, bright </span>galaxies<span> are spirals, barred spirals or ellipticals. Spiral </span>galaxies<span> have a bulge at the center and a flattened disk containing spiral arms.</span>
