1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
Verdich [7]
3 years ago
9

The side chain of histidine has a typical pKa value in the range of 6.5-7.4. However, when analyzing the pKa values in a particu

lar protein, scientists determined that one particular His residue has an unusually low pKa value of 4.8. Which of the following statements correctly explain this anomaly?
1) The microenvironment around a residue can impact its pKa value.
2) A positively charged amino acid must be in close proximity to this residue.
3) A negatively charged amino acid must be in close proximity to this residue.

Statements 1 and 2 are correct.
Statements 1 and 4 are correct.
Statements 1, 2, and 4 are correct.
Statements 2, 3, and 4 are correct.

4) This residue must be located on the surface of the protein.
Chemistry
1 answer:
Leona [35]3 years ago
8 0

Answer:

Statements 1 and 2 are correct.

Explanation:

The microenvironment around a amino acid residue can impact its pKa value according with the Born effect. If there is a positively charged environment, like in the second option, the pKa value will decrease, just as it happens in the histidine residue. So the correct answers are 1 and 2.

You might be interested in
When do epa’s refrigerant management regulations exempt refrigerant from the venting prohibition
Xelga [282]

The Environmental Protection Agency (EPA) refrigerant management regulations would exempt any refrigerant from venting problem when it determines that the refrigerant in an appliance do not pose a threat to the environment (surrounding) if released.

A refrigerant can be defined as any chemical substance that undergoes a phase change (liquid and gas) so as to enable the cooling and freezing of materials. They are typically used in air conditioners, refrigerators, water dispensers, etc.

In the United States of America, the Environmental Protection Agency (EPA) is a governmental agency which was established by U.S Congress and it is saddled with the responsibility of overseeing all aspects of pollution, environmental clean up, degradation, pesticide use, contamination, and hazardous waste spills. Also, EPA research solutions, policy development, and enforcement of regulations through the resource Conservation and Recovery Act.

Simply stated, the Environmental Protection Agency (EPA) is the governmental agency set up to ensure that various industries, factories and people comply with laws and regulations concerning the environment.

In conclusion, appliances such as a refrigerator, air conditioner (AC), etc., whose refrigerants do not pose a threat (potentially cause damage) to the environment if released are typically exempted by the EPA's refrigerant management regulations.

6 0
3 years ago
When a __________ is completely dissolved in a __________, a solution is formed.
ValentinkaMS [17]
When a solute is completely dissolved in a solvent, a solution is formed.
8 0
3 years ago
The proteins of all living things require<br> geometry of amino acids.
Dmitry [639]

As the building blocks of proteins , amino acids are linked to almost every life process, but they also have key roles as precursor compounds in many physiological processes.

8 0
3 years ago
Read 2 more answers
A generator makes electricity from _____.
marysya [2.9K]

Answer: kinetic energy

Explanation: searched it up

6 0
3 years ago
Read 2 more answers
Describe how transverse waves can be produced on a rope
goblinko [34]
Move your rope up and down and that will create transverse waves.
Was this helpful?
4 0
3 years ago
Other questions:
  • How am I ment to label this diagram
    13·1 answer
  • What relationship do you see between an electronic configuration of an element to its most common ion formed?
    8·2 answers
  • The symbols given to elements are always directly related to their chemical names
    9·1 answer
  • Water acts as a(n) _____. solvent solute organic substance ionic compound
    10·2 answers
  • What is the difference between relative humidity and humidity?
    10·1 answer
  • Look at the reaction below and state which direction the reaction would shift:
    12·1 answer
  • Chemistry Problem<br><br>1234567890-
    10·2 answers
  • helppppp. which of the following statements regarding physical and chemical changes is true? a. both physical and chemical chang
    7·2 answers
  • A chemical reaction is expected to produce 0.068 moles of oxygen. What volume in liters will be occupied by this gas sample at 2
    11·1 answer
  • Sn + 2HCI --&gt; SnCl2 + Hz
    8·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!