Which of the following statements about functional nuclear domains is correct? Choose all that apply.-There is a single function
al domain where all nuclear activity occurs.-They provide localized regions of function.-They are sites of low activity.-They are highly discrete and organized.-They refer to protein domains encoded by genomic DNA.
The correct answers are: They provide localized regions of function and They are highly discrete and organized
Nuclear domains or bodies are membraneless structures within the nucleus that make nucleus compartmentalized. The function of these “compartments” is to enhance the efficiency nuclear processes. Nuclear bodies include:
• the nucleolus-the place where ribosome biogenesis occurs.
• Cajal bodies- consist of proteins and RNA; its functions are associated with telomerase assembly; in cells that divide rapidly
• splicing speckles –contain RNA splicing factors
• promyelocytic leukemia protein nuclear bodies-involved in programmed cell death; control cell division.
The decoding of information in a cell's DNA into proteins begins with a complex ... use different sets of catalysts to express only specific portions of these instructions to ... that the process of DNA replication be as accurate as possible (Figure 1). ... number depends on how active a particular cell is in synthesizing proteins.
