When osteocytes were experimentally destroyed, the bones showed a significant increase in bone resorption, decreased bone formation, trabecular bone loss, and loss of response to unloading. ... The osteocyte is an important regulator of bone mass and a key endocrine regulator of phosphate metabolism.
Opening the bracket is the first order in solving arithmetic from BODMAS but to do that in this case we need to add 4^3 and 9 which first requires us to find 4^3