Someone culture can impact how someone interacts with someone because of beliefs, culture and how they practice there culture. there are many different cultures and we all interact different with the different cultures.
A bacterial infection hope this helped
The brain gets used to you taking the drug. Some drugs will affect your neurotransmitters, or messages that get sent to your brain that regulates how we think or feel. You will eventually become dependent on the drug so if you stop you might feel sick or go through "withdrawal". Which people dont want to go through so they will continue to take the drug.