All categories

3 years ago

The classical pathway for complement activation is initiated by

1 answer:

maks197457 [2]3 years ago

4 0

Answer: The classical complement pathway for complement activation is initiated by antigen-antibody complexes with the antibody isotypes IgG and IgM.

Explanation: The classical complement pathway typically requires antigen-antibody complexes (immune complexes) for activation (specific immune response), whereas the alternative pathway can be activated by C3 hydrolysis, foreign material, pathogens, or damaged cells.

After activation, a series of proteins are recruited to generate C3 convertase, which cleaves the C3 protein. The C3b component of the cleaved C3 binds to C3 convertase to generate C5 convertase, which cleaves the C5 protein. The cleaved products attract phagocytes to the site of infection and tags target cells for elimination by phagocytosis. In addition, the C5 convertase initiates the terminal phase of the complement system, leading to make appear the membrane attack complex. The membrane attack complex creates a pore on the target cell's membrane, inducing cell lysis and death.

You might be interested in

You are writing a report about space travel. Where would be the best place to find information? (2 points)

Harrizon [31]

Answer: Contact the National Aeronautics and Space Association

Explanation:

The National Aeronautics and Space Association is an independent organization in US which aims to enable a safe, secure, efficient space journey and launch of new satellites, spacecraft beyond the earth's orbit. It can give better information for the space travel already conducted by the astronauts. Thus will help in writing the report as it is the best place to find the information.

5 0

2 years ago

Read 2 more answers

A student standing on the ground throws a ball straight up. The ball leaves the student's hand with a speed of 19.0 m/s when the

german

Answer: 4 s

Explanation:

Given

The ball leaves the hand of student with a speed of $u=19\ m/s$

When the hand is $h=2.5\ m$ above the ground

Using the equation of motion we can write

$h=ut+\dfrac{1}{2}at^2$

Substitute the values

$\Rightarrow 2.5=-19t+0.5\times 9.8t^2\\\Rightarrow 4.9t^2-19t-2.5=0\\\\\Rightarrow t=\dfrac{19\pm \sqrt{(-19)^2-4\times 4.9\times (-2.5)}}{2\times 19}\\\Rightarrow t=4.0049\quad [\text{Neglecting the negative value of }t]$

Thus, the ball will take 4 s to hit the ground.

5 0

2 years ago

A solenoid of length 18 cm consists of closely spaced coils of wire wrapped tightly around a wooden core. The magnetic field str

Kisachek [45]

Answer:

$B_2 = 1.71 mT$

Explanation:

As we know that the magnetic field near the center of solenoid is given as

$B = \frac{\mu_0 N i}{L}$

now we know that initially the length of the solenoid is L = 18 cm and N number of turns are wounded on it

So the magnetic field at the center of the solenoid is 2 mT

now we pulled the coils apart and the length of solenoid is increased as L = 21 cm

so we have

$\frac{B_1}{B_2} = \frac{L_2}{L_1}$

now plug in all values in it

$\frac{2.0 mT}{B_2} = \frac{21}{18}$

$B_2 = 1.71 mT$

3 0

2 years ago

What is the difference between delta and harbor?

Margarita [4]

The difference between delta and harbor is is that delta is the fourth letter of the modern greek alphabet while harbor is a sheltered expanse of water, adjacent to land, in which ships may dock or anchor, especially for loading and unloading.

5 0

3 years ago

What is needed to set a body in motion

kumpel [21]

Answer:

Newtons law

Explanation:

According to this law, a body at rest tends to stay at rest, and a body in motion tends to stay in motion, unless acted on by a net external force.

3 0

3 years ago