A series of logical steps followed to solve problems.
The horse and donkey, though closely related by sharing a common ancestor, are different species. They have different number of chromosomes hence pairing of homologous chromosomes during fusion of gametes becomes complicated. The mule will have an extra chromosome from the horse hence will have abnormalities such as sterility. A Mule is unable to reproduce due to this same phenomenon. Homologous chromosomes are not well paired for meiosis I.
The main difference between haploid and diploid cells is the number of chromosome sets found in the nucleus. Diploid cells have two sets while haploid cells only contain one set.
