Answer:
The correct answer is "5-1-3-2-4".
Explanation:
Internalization of LDL particles into cells, is needed to form the intracellular vesicles known as endosomes. The order of events that allow for this process are:
5) LDL receptors migrate to the cell surface and cluster in clathrin-coated pits. Clathrin acts directing the receptors to the cell membrane region where endosomes are formed.
1) A combination of cholesterol and apolipoprotein binds to LDL receptors and becomes internalized as endocytotic vesicles. Once the receptors are in the proper cell membrane region, cholesterol and apolipoprotein are bound and internalized.
3) Several endocytotic vesicles fuse to form an endosome.
2) The environment of the endosome becomes acidic, which causes the LDL to dissociate from its receptor; additionally, the endosome fuses with a lysosome. LDL should be dissociated from its receptor since it is going to be degraded in the following step.
4) The LDL particle is degraded by the lysosome. This takes place after endocytosis, when LDL particles are transported into lysosomes once they are fused, cleaving the cholesterol esters into cholesterol and fatty acids.
C)1125 J because the formula for kinetic energy is 1/2 multiplied by mass multiplied by volume to the second power. So 1/2 multiplied by 10 multiplied by 15 to the second power is 1125 if that makes since.
Skin pigments actually protect us from ultraviolet rays!
Answer: The effects of which are devastating to human life, flora and fauna, which depend on these resources for their survival. Contamination of water causes disruptions of food chains and destruction of ecosystems. A deadly by-product of this water pollution is the spread of water-borne diseases such as cholera, typhoid etc.
Explanation:
