You know from trigonometry that AB = 15 units, so the area of the larger triangle ACB is (1/2)*15*15 = 112.5 units^2.
Then the area of triangle ADE is
.. (112.5 -62.5) = 50 . . . . units^2
F(x) = (-x²+x+20) / (x+4)
-x²+x+20 | x+4
+x²+4x -x+5
\\\\ 5x+20
-5x-20
\\\\\\\\\
f(x) = (x+4)(-x+5) / (x+4)
f(x) = (-x+5)
The graph is a decreasing line, with origin from 5.
If you cut it in half every two hours, the answer will be 10.9375 mg.